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5-in-1 vaccine adverse reactions since 2002 UK (diphtheria, pertussis, polio, tetanus, hib) As of Feb 2014; obtained from the MHRA Yellow Card scheme dtpa_ipv_hib.pdf
Acute renal failure after influenza vaccination This is the fourth case report of acute renal failure after influenza vaccination in patients on statins therapy. J Prev Med Hyg. 2014 Mar;55(1):31-2.
Adverse Events Associated With Childhood Vaccines Other Than Pertussis and Rubella The committee found that the evidence favored acceptance of a causal relation between diphtheria and tetanus toxoids and Guillain-Barré syndrome and brachial neuritis, between measles vaccine and anaphylaxis, between oral polio vaccine and Guillain-Barré syndrome, and between unconjugated Hib vaccine and susceptibility to Hib disease. The committee found that the evidence established causality between diphtheria and tetanus toxoids and anaphylaxis, between measles vaccine and death from measles vaccine—strain viral infection, between measlesmumps-rubella vaccine and thrombocytopenia and anaphylaxis, between oral polio vaccine and poliomyelitis and death from polio vaccine—strain viral infection, and between hepatitis B vaccine and anaphylaxis. JAMA. 1994;271(20):1602-1605
Adverse events following MMR vaccinations Canada 2011 There are significantly elevated risks of primarily emergency room visits approximately one to two weeks following 12 and 18 month vaccination. PLoS One. 2011; 6(12): e27897
Affect of Aluminium on living organisms Aluminium is contained in most vaccine adjuvants Journal of Toxicology Volume 2014 (2014), Article ID 491316, 27 pages 491316.pdf
Aluminium adjuvants from vaccines linked to autism tomljenovic_2011.pdf
Aluminium adjuvants risk chronic fatigue syndrome This case has highlighted potential dangers associated with aluminium-containing adjuvants and we have elucidated a possible mechanism whereby vaccination involving aluminium-containing adjuvants could trigger the cascade of immunological events which are associated with autoimmune conditions including chronic fatigue syndrome and macrophagic myofasciitis. Med Hypotheses. 2009 Feb;72(2):135-9.
Aluminium containing vaccines linked to autism MMR vaccine also implicated; possibility of aluminium being even worse than mercury Entropy 2012, 14, 2227-2253 entropy-14-02227-v2.pdf
Aluminium hydroxide toxicity from vaccines J Inorg Biochem. 2009 Nov;103(11):1555-62
Aluminium toxicity in humans and animals, vaccine adjuvants, and autoimmunity (incl autism) In young children, a highly significant correlation exists between the number of pediatric aluminum-adjuvanted vaccines administered and the rate of autism spectrum disorders. Immunologic Research July 2013, Volume 56, Issue 2-3, pp 304-316
Another MMR / Measles vaccine link to autism J Biomed Sci. 2002 Jul-Aug;9(4):359-64. abnormal_measles-mumps-rubella_antibodies_and_cns_autoimmunity_in_children_with_autism.pdf
Antibody response does not equal immunity (immunogenicity, antibodies, mumps)) Though pro-vaccination, this study shows a lack of correlation between antibody titers and protection www.ncbi.nlm.nih.gov/pubmed/19320590
Assessing immunity from antibody titers inadequate to ascertain immunity (Measles) www.ncbi.nlm.nih.gov/pubmed/1492697
Asthma and vaccination status - vaccinated children more likely to have asthma? This study found that vaccinated children are up to 14 times more likely to suffer from asthma but the study authors say the reason was that those who were not vaccinated were also seeing their doctor less frequently and therefore less likely to be diagnosed. They believe just as many unvaccinated children may have asthma but have not been diagnosed as such. Am J Public Health. 2004 June; 94(6): 985–989
Autism may be linked to hyperimmune response to Measles virus in vaccine Pediatr Neurol. 2003 Apr;28(4):292-4.
Autism rate linked to vaccinations USA 2011 A positive and statistically significant relationship was found: The higher the proportion of children receiving recommended vaccinations, the higher was the prevalence of AUT or SLI. www.ncbi.nlm.nih.gov/pubmed/21623535 vaccine_and_autism_correlation_us_2011_j_tox_env_health.pdf
Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants It seems that the role of adjuvants in the pathogenesis of immune-mediated diseases can no longer be ignored, and the medical community must look towards producing safer adjuvants. Lupus February 2012 vol. 21 no. 2 118-120
Autoimmune disease caused by adjuvants Page of links to numerous studies www.vaccination-information-portal.com/autoimmune-diseases-caused-by-vaccines-vaccine-adjuvants
Blood mercury levels associated with ADHD Arch Toxicol. 2009 Nov;83(11):965-78
Breastfeeding helps prevent Rotavirus infections but does not offer complete protection 397-full.pdf
CDC: Vaccination not the same as Immunization Although persons often use vaccination and immunization interchangeably in reference to active immunization, the terms are not synonomous because the administration of an immunobiologic cannot be automatically equated with the development of adequate immunity. MMWR 43(RR01);1-38
Cervical cancer accounts for 1% of cancer deaths in UK women Cervical cancer is the 17th most common cause of cancer death among women in the UK (2012), accounting for 1% of all female deaths from cancer. www.cancerresearchuk.org/cancer-info/cancerstats/types/cervix/mortality/uk-cervical-cancer-mortality-statistics
Cervical cancer constitutes 2% of cancers diagnosed in UK women Around 3,100 women are diagnosed with cervical cancer in the UK each year. Overall, about 2 out of every 100 cancers diagnosed in women (2%) are cervical cancers. But it is the most common cancer in women under 35 years old. www.cancerresearchuk.org/about-cancer/type/cervical-cancer/about/cervical-cancer-risks-and-causes
Cervical cancer deaths dropped over 70% in last 40 years Mortality from cervical cancer has been declining for decades. [will HPV vaccines in future be credited with the improvement?] www.cancerresearchuk.org/cancer-info/cancerstats/types/cervix/mortality/uk-cervical-cancer-mortality-statistics
Chickenpox vaccination: risk of bias in studies Cochrane Review: Found protective effect from vaccines but also "dentified high or unclear risk of bias in two of the three included studies." Cochrane Database of Systematic Reviews 2014, Issue 6. Art. No.: CD001833
CNS demyelinating disease following vaccination Case Rep Neurol. 2015 Apr 11;7(1):78-83
CNS inflammation following HPV immuni-zation (side-effects, adverse events, SAE) We report five patients who presented with multifocal or atypical demyelinating syndromes within 21 days of immunization with the quadrivalent human papilloma virus (HPV) vaccine, Gardasil. Neurol Neuroimmunol Neuroinflammation 2014;1:e31 neurol_neuroimmunol_neuroinflamm-2014-fernandez-fournier-.pdf
Cochrane review on influenza vaccinations in healthy adults Influenza vaccines have a very modest effect in reducing influenza symptoms and working days lost in the general population, including pregnant women. No evidence of association between influenza vaccination and serious adverse events was found in the comparative studies considered in the review. This review includes 90 studies, 24 of which (26.7%) were funded totally or partially by industry. Out of the 48 RCTs, 17 were industry-funded (35.4%). Cochrane Database of Systematic Reviews 2014, Issue 3. Art. No.: CD001269 cd001269_abstract.pdf
Cochrane review: Rotavirus vaccines prevent rotavirus diarrhoea Cochrane Database of Systematic Reviews 2012, Issue 11. Art. No.: CD008521 cd008521_abstract.pdf
Diphtheria outbreak 1990s vaccination coverage 90% of children were vaccinated with 4 doses by school-age; mainly affected adults; case-fatality ratio was less than 5% www.cdc.gov/mmwr/preview/mmwrhtml/00022128.htm
Dr C Shaw interview: explains effects of aluminium on the human body link to youtube video www.youtube.com/watch?v=FfTo35UrFPA#t=15
DTP vaccination leads to higher mortality in African infants A study that shows vaccinated infants in Africa to have a 5x higher mortality than unvaccinated. www.sciencedirect.com/science/article/pii/S2352396417300464 1-s2-0-s2352396417300464-main.pdf
Effect of antipyretics on antibody response to vaccination Although febrile reactions significantly decreased, prophylactic administration of antipyretic drugs at the time of vaccination should not be routinely recommended since antibody responses to several vaccine antigens were reduced. Effect of prophylactic paracetamol administration at time of vaccination on febrile reactions and antibody responses in children: two open-label, randomised controlled trials
Eligibility for vaccine damage payments in the UK www.gov.uk/vaccine-damage-payment/eligibility
Evidence of Merck influencing vaccination policy making (HPV) www.ncbi.nlm.nih.gov/pmc/articles/PMC3483914/ screen_shot_2017-02-17_at_11-54-58.png
Example of vaccine-caused measles after MMR vaccine-associated measles in a two-year-old patient from British Columbia, Canada, in October 2013, who received her first dose of measles-containing vaccine 37 days prior to onset of prodromal symptoms Eurosurveillance, Volume 18, Issue 49, 05 December 2013 art20649.pdf
Fever improves outcome from meningitis Patients with acute bacterial meningitis admitted to ICU had substantial morbidity and mortality. Those with low GCS or absence of fever have a particularly high risk of an adverse outcome. J Crit Care. 2014 Jun;29(3):347-50. doi: 10.1016/j.jcrc.2013.12.001.
Flu vaccination has no impact on absenteeism in UK schools www.ncbi.nlm.nih.gov/pubmed/27609702
Flu vaccine 3% effective in UK 2014/2015 season Press release on gov.uk website www.gov.uk/government/news/flu-vaccine-shows-low-effectiveness-against-the-main-circulating-strain-seen-so-far-this-season eurosurveillance_volume_20_issue_5_05_february_2015_.pdf
Flu vaccine can increase risk of otitis media Live attenuated influenza vaccines may increase bacterial transmigration to the middle ear and could thus increase risk of clinically relevant acute otitis media. www.ncbi.nlm.nih.gov/pubmed/25505300
Flu vaccine shows no protective effect in small New Zealand study 2012 Flu vaccine shows no protective effect in small NZ study: This audit shows that the 2012 seasonal influenza vaccine did not provide significant protection against the H3N2 influenza strain... Vaccination did not alter the clinical course or final outcome in patients infected with H3N2 influenza. www.ncbi.nlm.nih.gov/pubmed/25146857
Flu vaccines effectiveness and data quality (cochrane, influenza) Influenza vaccinations are at most moderately effective and even when industry-sponsored studies are included - Cochrane review www.ncbi.nlm.nih.gov/pubmed/20614424
Gardasil increased risk of autoimmune adverse events (study,2014,hpv) A case-control study of quadrivalent human papillomavirus vaccine-associated autoimmune adverse events.<br /><br />Gardasil makes you 5 times more likely to get Lupus, 4.6 times more likely to get gastroenteritis, 2.5 times more likely to get arthritis, 4 times more likely to get vasculitis, 1.8 times more likely to suffer Central Nervous System related problems and 8 times more likely to get alopecia as consequences of Serious Autoimmune Adverse Reactions, according to recent study www.ncbi.nlm.nih.gov/pubmed/25535199
Girl, five, dies from a strain of the flu she was vaccinated against Mail online 25 Jan 2014
Guillain-Barré syndrome after influenza vaccination in adults Influenza vaccination is associated with a small but significantly increased risk for hospitalization because of GBS. Arch Intern Med. 2006 Nov 13;166(20):2217-21
Half of pertussis patients fully vaccinated in Canadian study As many vaccinated as unvaccinated children got pertussis but vaccinated ones tend to be much older, suggesting the vaccine protects for a number of years. www.ncbi.nlm.nih.gov/pmc/articles/PMC3931923/
Health Protection Agency: narcolepsy risk from pandemic A/H1N1 2009 flu vaccine (Pandemrix) The increased risk of narcolepsy after vaccination with ASO3 adjuvanted pandemic A/H1N1 2009 vaccine indicates a causal association, consistent with findings from Finland. Because of variable delay in diagnosis, however, the risk might be overestimated by more rapid referral of vaccinated children. BMJ 2013;346:f794
Hep B vaccinations: unclear effect (Cochrane review 2008, hepatitis) Twelve trials were eligible. All had high risk of bias and reporting was inconsistent. Cochrane Database of Systematic Reviews 2008, Issue 3. Art. No.: CD006481
Hepatitis B vaccination cause of autoimmune disease? Med Hypotheses. 2008;70(2):346-8. Epub 2007 Jul 13.
Hepatitis b vaccination linked to autism (USA 2010) J Toxicol Environ Health A. 2010;73(24):1665-77.
Hepatitis B vaccine (hep b) autoimmune hazards This paper points out that information on the safety of hepatitis B vaccine (HBV) is biased as compared to classical requirements of evidence-based medicine (EBM) Autoimmun Rev. 2005 Feb;4(2):96-100.
Hib cases among fully vaccinated children In 2002, 85% of Hib cases were in fully vaccinated children in England and Wales www.vaccination-information-portal.com/wp-content/uploads/HPA.pdf
Hib cases are underreported in the age group targeted for vaccination Study compared active and passive surveillance data following the introduction of Hib vaccinations in the UK. www.ncbi.nlm.nih.gov/pmc/articles/PMC27486/
Hib cases reduced in both the vaccinated and unvaccinated after vaccination campaign After Hib vaccine was introduced marked reductions were observed in the number of cases of Hib disease in children under five years of age. Disease rates also fell in older children and adults who had not been immunised because the number of children carrying Hib bacteria, and therefore able to infect other people, fell. www.vaccination-information-portal.com/wp-content/uploads/HPA.pdf
Hib vaccine and diabetes risk: causal relationship likely 54 more cases of diabetes per 100,000 in vaccine group BMJ. Oct 23, 1999; 319(7217): 1133. 1133p.pdf
Hib vaccine: increased risk of diabetes Autoimmunity. 2002 Jul;35(4):247-53.
High risk of a autoimmune complications from vaccine adjuvants Lupus. 2012 Feb;21(2):146-52.
High statistically significant correlation between increasing number of vaccine doses and increasing infant mortality rates A Corrigendum published later on revealed the author to be associated with vaccination awareness organisation. However the study and its results were not disputed to our knowledge. Hum Exp Toxicol. Sep 2011; 30(9): 1420–1428.
HPV not main cause for cervical cancer HPV is not the main cause of premalignant and malignant cervical lesions www.ncbi.nlm.nih.gov/pubmed/25509977
HPV vaccination side-effects Study suggests causal link possible and calls for urgent follow-up Brinth LS, et al. Vaccine. 2015.
HPV vaccine adverse reactions since 2006 UK As of Feb 2014; obtained from the MHRA Yellow Card scheme human_papilloma_virus_dap.pdf
HPV vaccine severe side effects case series and literature review Palmieri, B., Poddighe, D., Vadalà, M. et al. Immunol Res (2016).
HPV vaccine studies largely inadequate (Gardasil, Cervarix) Inadequate efficacy and safety trials give false hope for HPV vaccinations. www.ncbi.nlm.nih.gov/pubmed/23016780
Inactivated influenza vaccine increases risk of non-influenza respiratory illness in children vaccinated children were 4.4 times more likely to get ill from non-influenza RI and no less likely to get influenza 1778-full.pdf
Increased rate of hospitalisation after vaccinations in Canda There are significantly elevated risks of primarily emergency room visits approximately one to two weeks following 12 and 18 month vaccination. PLoS One. 2011; 6(12): e27897.
Influenza (flu) vaccinations linked to fetal loss in pregnant women het.sagepub.com/content/32/5/464
Influenza (flu) vaccinations to protect from exacerbation of asthma There was no significant reduction in the number, duration or severity of influenza-related asthma exacerbations. Cochrane Database of Systematic Reviews 2013, Issue 2. Art. No.: CD000364
Influenza despite high antibody titers (immunogenicity, immunity, protection) www.ncbi.nlm.nih.gov/pubmed/2230050
Influenza vaccine adverse reactions since 1963 UK (flu) As of Feb 2014; obtained from the MHRA Yellow Card scheme influenza.pdf
Influenza vaccine and asthma hospitalization (flu) No protection from the vaccine but vaccinated children much more likely to be hospitalized Allergy Asthma Proc. 2012 Mar-Apr;33(2):e23-7. doi: 10.2500/aap.2012.33.3513
Is autism a form of mercury poisoning USA 2001 Med Hypotheses. 2001 Apr;56(4):462-71.
Is infant immunization by breastfeeding possible? Philos Trans R Soc Lond B Biol Sci. 2015 Jun 19;370(1671) breastfeedingimmunization.pdf
JCVI accused of unethical and dishonest behaviour (fraud, bias) An analysis of meeting transcripts accuses the JCVI and DH of concealing safety concerns, selective use of science, being more concerned with publicity than safety and discouraging vaccine safety research. bsem-2011.pdf
Journal editors criticise on industry / pharmaceutical industry Selection of links Journal Editors Criticise Industry
Limit durability of pertussis vaccine immunity USA 2012 Despite widespread childhood vaccination against Bordetella pertussis, disease remains prevalent. It has been suggested that acellular vaccine may be less effective than previously believed. cid.oxfordjournals.org/content/54/12/1730
Little evidence of a herd effect from influenca (flu) vaccinations In summary, herd effects are assumed with influenza vaccine programmes, but there are few studies that quantify the herd effect of vaccination. We found low-level evidence supporting a herd effect of vaccination on influenza virus infection in contacts of vaccinated persons. Further rigorous studies are needed in order to better understand under which circumstances vaccination may prevent influenza and its complications in contacts. Eurosurveillance, Volume 21, Issue 42, 20 October 2016
Live flu vaccine shedding study by MedImmune Study by manufacturer of Fluenz 2011: 79% of children shed live virus mainly up to 11 days. www.ncbi.nlm.nih.gov/pubmed/21513761
Low antibody levels in Germany but no outbreak (diphteria, 1990s) While the Diphtheria outbreak was happening in the former Soviet countries, Germany had no outbreak, despite only 1.5% having "protective" antibody levels in 1994. www.ncbi.nlm.nih.gov/pubmed/12736822
Low rate of Tetanus mortality in the UK On average fewer than 1 people die of Tetanus in the UK per year. The last time a child died was 1973. - Office of National Statistics data
Low-birth-weight babies at risk from vaccinations (premature, infants, adverse reactions) Study found increased need of life support in very premature and low-birth-weight babies after routine vaccinations adverse_events_after_routine_immunization_of_extremely_low-birth-weight_babies0615jama.pdf
Maternal antibodies in infants - vaccinated vs unvaccinated mothers Antibodies last longer in infants born to unvaccinated mothers. J Infect Dis., May 8, 2013 j_infect_dis--2013-gans-infdis_jit144.pdf
Measles among immunised healthcare workers with high antibody titers "Eight HCWs were notified as measles cases; 6 were vaccinated with measles vaccine twice, 1 was vaccinated once, and 1 was unvaccinated. All 6 twice-vaccinated cases had high avidity and PRN titers." J Infect Dis (2016) 214 (12): 1980-1986
Measles complications linked to malnutrition, underlying conditions and lack of vitamin A WHO information taken from its website: "Severe measles is more likely among poorly nourished young children, especially those with insufficient vitamin A, or whose immune systems have been weakened by HIV/AIDS or other diseases." www.who.int/mediacentre/factsheets/fs286/en/
Measles continues to break out in highly vaccinated populations 1994 study found 18 reports of measles outbreaks in very highly immunized school populations where up to 99.8% of students were "immunised" www.ncbi.nlm.nih.gov/pubmed/8053748
Measles in highly vaccinated population - failure of herd immunity effect Even with very high levels of coverage, outbreaks occur and mainly affect the vaccinated. www.ncbi.nlm.nih.gov/pubmed/8053748
Measles outbreak - 93.4% of population "immune" Of 28 cases, 8 were vaccinated twice; 4 more vaccinated once. Eurosurveillance, Volume 22, Issue 23, 08 June 2017
Measles Outbreak Among Previously Immunized Healthcare Workers, the Netherlands, 2014 "All 6 twice-vaccinated cases had high avidity and PRN titers. None reported severe measles or onward transmission. Two of 4 investigated twice-vaccinated cases had pre-illness PRN titers of >120 mIU/mL. Among 106 potentially exposed HCWs, the estimated effectiveness of 2 doses of measles vaccine was 52%" The Journal of Infectious Diseases, Volume 214, Issue 12, 15 December 2016, Pages 1980–1986
Measles spread by the VACCINATED and evidence for vaccine failure Clin Infect Dis. (2014) 58 (9): 1205-1210
Measles Statistics for England and Wales https://www.gov.uk/government/collections/measles-guidance-data-and-analysis
Measles vaccination coverage, notified cases and mortality Overlay of graphs showing development since Wakefield report
Measles vaccine shedding; virus RNA in urine JOURNAL OF CLINICAL MICROBIOLOGY, Sept. 1995, p. 2485–2488 detectionofmeaslesinvaccinerecipients.pdf
Medical journal editors criticise own industry (funding, bias, marketing) “Journals have devolved into information laundering operations for the pharmaceutical industry” journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020138#pmed-0020138-b21 journal-pmed-0020138.pdf
Medical journals conflict of interest (2) (bias, funding) Editors, Publishers, Impact Factors, and Reprint Income PLoS Med. 2010 Oct; 7(10): e1000355.
Medical journals conflict of interest (bias, funding) The Influence of Industry-Supported Randomised Trials on Journal Impact Factors and Revenue – Cohort Study PLoS Med. 2010 Oct; 7(10): e1000354
Meingococcal cases also reduced in the unvaccinated following vaccination campaigns The reduction in unvaccinated children and adults was put down to an indirect protective effect from the vaccine. www.bmj.com/content/326/7385/365.1
Men C / Hib vaccine adverse reactions since 2006 UK (meningococcal) As of Feb 2014; obtained from the MHRA Yellow Card scheme meningococcal_group_c_haemophilus_influenzae_type_b.pdf
Men C vaccine adverse reactions since 1999 UK (meningococcal) As of Feb 2014; obtained from the MHRA Yellow Card scheme - see also Men C/Hib document meningococcal_group_c.pdf
Meningitis and meningococcal disease risk factors A selection of links to studies on PubMed. www.vaccination-information-portal.com/risk-factors-for-meningococcal-disease-and-meningitis
Meningitis Charity pushing for Men B vaccine receives funding from vaccine manufacturer The meningitis charity that has been campaigning to have Novartis' Bexsero vaccine introduced in the UK receives funding from Novartis. meningitistrust_2013.pdf
Meningococcal disease and environmental factors Epidemiol Infect. 1994 Apr; 112(2): 315–328